Mounjaro, strictly speaking, is not a GLP-1 receptor agonist but a twin GIP/GLP-1 receptor agonist; it mimics the operate of a second hormone, which can be possibly the secret of its effectiveness.Jun 22, 2008 #5 In accordance with the product data, Metformin can assist with weight loss. In Dr Anne L Peter's e book "Conquering Diabetes" she states